Molecular neurodevelopment: An in vivo31P-1H MRSI study To view the full article click here to login Gerald Goldstein1, Kanagasabai Panchalingam2, Richard J. McClure2, Jeffrey A. Stanley6,Vince D. Calhoun7,8, Godfrey D. Pearlson9, and Jay W. Pettegrew2,3,4,5 1 VA Pittsburgh Healthcare System, Pittsburgh, PA2 Department of Psychiatry, University of Pittsburgh School of Medicine, University of Pittsburgh,Pittsburgh, PA3…
Read MoreSolid State 31p and 27 Al NMR Studies of Model Membranes and Mammalian Brain: Possible Implications for Alzheimer’s Disease
J. W. Pettegrew and K. Panchalingam Introduction and Background A. Chemical Characteristics Aluminum is the third most abundant element in the earth’s crust (over 8% (W/W) of the earth’s crust) following oxygen (46.6%) and silicon (27.7%). Aluminum bonds to oxygen and silicon in aluminosilicate granites and clays (Bailar et al 1984; Cotton et al…
Read More31p NMR of Brain Aging and Alzheimer’s Disease
31p NMR of Brain Aging and Alzheimer’s Disease
Read MoreA Preliminary 31p MRS Study of Autism: Evidence for Undersynthesis and Increased Degradation of Brain Membranes – LOGIN TO VIEW
To view the full article click here to login Nancy J. Minshew, Gerald Goldstein, Stephen M. Dombrowski,Kanagasabai Panchalingam, and Jay W. Pettegrew In this pilot study, brain high energy phosphate and membrane phospholipid metabolism wereinvestigated in the dorsal prefrontal cortex of II high-functioning autistic adolescent andyoung adult men (the age range is 12-36 years) and…
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